Peptide Synthesis Reagents & Peptides
Peptide Synthesis Reagents, Coupling Reagents, Custom Synthesized Peptides, Resins and Related Products
Comprehensive Solutions for Peptide Synthesis and Research
Peptide synthesis is an essential process in modern life science research, biotechnology, pharmaceutical development, and biochemical analysis. Synthetic peptides are widely used to investigate protein structure and function, study molecular interactions, explore cellular signaling pathways, and develop innovative research applications. Achieving successful peptide synthesis requires carefully selected amino acids, protecting groups, coupling reagents, solvents, linkers, and solid-phase resins that support each stage of the synthesis process.
AGTC Bioproducts Ltd supplies an extensive range of peptide synthesis reagents, coupling reagents, amino acid derivatives, resins, linkers, solvents, and specialized biochemical tools. Our portfolio is designed to support researchers and laboratories working with both routine peptide synthesis procedures and more complex custom peptide development projects.
We supply a wide selection of FMOC amino acids and modified amino acids, together with essential solvents such as N-methyl-2-pyrrolidone (NMP), dimethylformamide (DMF), piperidine, and DMF/piperidine premixes. Our range also includes amino acid derivatives, including FMOC- and BOC-protected compounds, specialized linkers, solid-phase synthesis resins such as WANG and TentaGel, and various coupling reagents used throughout peptide synthesis workflows.
In addition to individual synthesis reagents, we offer peptide synthesis services, custom synthesized peptides, and an extensive selection of ready-made, off-the-shelf peptides. Whether you require individual amino acid building blocks, specialized coupling chemistry, solid-phase synthesis materials, or a complete custom peptide sequence, AGTC Bioproducts provides a broad range of products and services to support your research requirements.
In fact, we aim to provide almost everything you need to synthesize, modify, purify, or purchase a peptide through a comprehensive selection of laboratory products and peptide-related services.
High-Quality Peptide Synthesis Reagents
The quality of starting materials and chemical reagents is a critical factor in successful peptide synthesis. Reagent purity, solvent quality, moisture content, and storage conditions can all influence reaction efficiency, synthesis performance, and the quality of the resulting peptide.
At AGTC Bioproducts, our peptide synthesis reagents are purified to the high standards required for reliable synthesis and excellent yields. Particular attention is given to solvent quality and product handling to help maintain the chemical integrity of the supplied materials.
Water content is minimized in our solvents to support peptide synthesis reactions in which moisture can interfere with reagent activity and coupling efficiency. Furthermore, containers are purged with nitrogen and securely sealed to help protect products from exposure to moisture and atmospheric contaminants, supporting extended shelf life when products are stored under appropriate conditions.
These quality-oriented measures are particularly important for laboratories performing solid-phase peptide synthesis (SPPS), where multiple chemical reactions must take place in a controlled and reproducible manner.
FMOC Amino Acids and Modified Amino Acids
FMOC-protected amino acids are among the most important building blocks used in modern solid-phase peptide synthesis. The FMOC (9-fluorenylmethoxycarbonyl) protecting group temporarily protects the amino functionality of an amino acid during peptide chain assembly.
In conventional FMOC-based solid-phase peptide synthesis, amino acids are incorporated sequentially onto a growing peptide chain attached to a solid support. The temporary FMOC protecting group is removed under appropriate conditions, allowing the next amino acid to be coupled.
This strategy provides researchers with a practical and widely used approach for preparing peptides with defined amino acid sequences.
AGTC Bioproducts supplies a wide range of FMOC amino acids and modified amino acids to support different peptide synthesis requirements. Modified amino acids are particularly useful when researchers need to introduce specific structural or functional properties into a peptide sequence.
Depending on the selected building block, modifications can help investigate peptide conformation, stability, molecular recognition, biological activity, and interactions with other biomolecules.
Our range of FMOC amino acids and modified amino acids provides essential starting materials for researchers working on synthetic peptides, peptide analogues, biochemical investigations, and specialized peptide development.
Amino Acid Derivatives and Protecting Groups
Amino acid derivatives are essential components of peptide synthesis because they allow specific functional groups to be protected during chemical reactions. Protecting groups help control the order and selectivity of chemical transformations, reducing unwanted side reactions during peptide assembly.
Our portfolio includes different amino acid derivatives, including FMOC- and BOC-protected amino acids.
FMOC and BOC are two widely used protecting group strategies in peptide chemistry:
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FMOC (9-Fluorenylmethoxycarbonyl): Commonly used in solid-phase peptide synthesis, particularly for synthesis strategies involving temporary protection of the amino group under basic deprotection conditions.
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BOC (tert-Butoxycarbonyl): Another important amino-protecting group used in peptide and organic synthesis, generally removed under acidic conditions.
The selection of an appropriate protecting group depends on the synthesis strategy, chemical compatibility, amino acid structure, and desired peptide modification.
These derivatives provide researchers with flexibility when designing peptide sequences and planning different synthetic approaches.
Coupling Reagents for Peptide Synthesis
Peptide coupling is a fundamental chemical step in which two amino acids are joined through the formation of a peptide bond. In synthetic peptide production, coupling reagents facilitate the activation of the carboxyl group of an amino acid, allowing it to react with the free amino group of another amino acid.
Efficient coupling chemistry is important because incomplete reactions can lead to deletion sequences and other impurities in the final peptide product.
AGTC Bioproducts offers coupling reagents and related additives used in peptide synthesis workflows. These reagents support the formation of peptide bonds during sequential amino acid incorporation and are relevant to both routine laboratory synthesis and more demanding peptide preparation procedures.
The appropriate coupling system depends on several factors, including amino acid structure, steric hindrance, sequence composition, solvent compatibility, and the selected synthesis protocol.
Researchers can explore our range of coupling reagents and additives to identify suitable chemical solutions for their peptide synthesis applications.
Solvents, Scavengers and Liquid Reagents
Solvents and liquid reagents play an essential role in peptide synthesis by providing the chemical environment required for amino acid activation, coupling, deprotection, and other synthesis operations.
Our range includes important solvents and liquid reagents such as:
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N-Methyl-2-pyrrolidone (NMP): A polar aprotic solvent used in peptide synthesis and other chemical applications.
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Dimethylformamide (DMF): A widely used solvent in solid-phase peptide synthesis because of its ability to dissolve many peptide synthesis reagents.
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Piperidine: Commonly used for FMOC group removal during solid-phase peptide synthesis.
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DMF/Piperidine Premixes: Convenient solvent formulations combining DMF and piperidine for applications involving FMOC deprotection.
Scavengers are also important in peptide synthesis and related chemical workflows. They can help control reactive intermediates and unwanted chemical species generated during specific reactions, depending on the synthesis strategy.
Solvent purity and moisture content are particularly important considerations when selecting liquid reagents. Minimizing water content helps maintain suitable reaction conditions, while appropriate packaging and storage contribute to product stability and performance.
Resins and Loaded Resins for Solid-Phase Peptide Synthesis
Solid-phase peptide synthesis is one of the most widely used approaches for producing synthetic peptides. In this technique, the growing peptide chain is attached to an insoluble solid support, allowing sequential reactions to take place while excess reagents and reaction by-products can be removed through washing.
The choice of resin is an important factor because the solid support can influence peptide loading, synthesis conditions, cleavage chemistry, and the final characteristics of the resulting peptide.
AGTC Bioproducts offers different peptide synthesis resins, including WANG and TentaGel resins, together with loaded resins for specialized synthesis requirements.
WANG Resin
WANG resin is a commonly used solid support in FMOC-based peptide synthesis, particularly for the preparation of peptides with a C-terminal carboxylic acid following appropriate cleavage conditions.
Its application in solid-phase peptide synthesis makes it an important material for researchers preparing synthetic peptides with defined sequences.
TentaGel Resin
TentaGel resins are polymer-supported materials used in combinatorial chemistry and solid-phase synthesis. Their structure combines a solid polymer support with a polyethylene glycol-based component, providing properties relevant to different synthetic applications.
These resins are useful in peptide chemistry and research workflows requiring suitable solid supports for chemical modification and molecular library preparation.
Loaded Resins
Loaded resins contain an amino acid or another suitable starting component already attached to the solid support. They can simplify the initial stage of peptide synthesis and provide researchers with a ready-to-use starting material for subsequent chain assembly.
The choice between conventional and loaded resins depends on the peptide sequence, synthesis strategy, and experimental requirements.
Linkers and Solid-Phase Linkers
Linkers connect the growing peptide chain or starting amino acid to the solid support during solid-phase peptide synthesis.
Their chemical structure is important because it influences the attachment of the target molecule to the resin and the conditions required for peptide cleavage at the end of the synthesis.
Different linker chemistries are selected according to the desired C-terminal functionality and cleavage strategy. Appropriate linker selection is therefore an important consideration when planning peptide synthesis, particularly for sequences requiring specific terminal chemical groups.
Our product range includes linkers and solid-phase linkers designed to support different peptide synthesis approaches and related chemical applications.
Custom Synthesized Peptides and Contract Peptide Synthesis
Not every research project can be supported by commercially available peptide sequences. Some experiments require specific amino acid compositions, modified residues, particular sequence lengths, or specialized molecular characteristics.
To address these needs, AGTC Bioproducts also offers custom synthesized peptides and contract peptide synthesis services.
Custom peptide synthesis allows researchers to request peptides designed according to their individual experimental requirements. Instead of selecting only from existing commercial sequences, customers can request the preparation of peptides based on their desired amino acid sequence and specifications.
These services are relevant to research involving:
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Protein-protein interaction studies.
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Antibody development and epitope mapping.
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Molecular recognition and binding investigations.
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Cellular signaling and receptor-related research.
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Enzyme-substrate interaction studies.
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Peptide structure-function investigations.
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Biochemical and pharmaceutical research.
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Development and evaluation of peptide analogues.
The specific synthesis requirements depend on the target sequence and requested modifications. Researchers can contact AGTC Bioproducts to discuss their peptide requirements and request a quotation for custom synthesis.
Our objective is to provide access to peptide synthesis solutions that support both standard research applications and more specialized scientific projects.
Ready-Made Peptides and Off-the-Shelf Peptide Products
In addition to custom synthesis services, AGTC Bioproducts offers an extensive catalogue of ready-made peptides.
We have more than 400 commonly used peptides available in our inventory, providing researchers with convenient access to frequently requested peptide sequences without the need to initiate an individual custom synthesis project.
Our stock peptide selection is designed to support laboratories looking for established peptide products for molecular biology, biochemical studies, cellular research, and other life science applications.
Finding a specific peptide is straightforward. Customers can enter the complete amino acid sequence, or even part of the sequence, into the quick search box available on the website.
The search system allows users to identify matching peptide products and explore available catalogue options.
For sequences that are not available in the existing inventory, customers can request a quotation for custom peptide synthesis performed in our state-of-the-art laboratories.
This combination of ready-made peptides and customized synthesis options provides flexibility for different research requirements, from routine experiments to specialized peptide development.
Additional Products for Peptide Chemistry and Biochemical Research
Beyond conventional peptide synthesis reagents, our portfolio includes several additional product categories supporting specialized chemical and biochemical applications.
These include:
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Building Blocks and Peptidomimetics: Chemical building blocks and peptide-inspired structures used in the investigation and development of molecules with peptide-like properties.
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Carbohydrates: Specialized carbohydrate products for biochemical research and molecular investigations.
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Biochemical Tools: Research tools and reagents supporting a variety of biochemical applications.
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Immobilized Enzymes and Special Proteins: Products used in biochemical studies, enzyme-related research, and specialized protein applications.
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Natural Products and Biochemistry Tools: Materials supporting investigations of naturally occurring compounds and biochemical mechanisms.
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PEG Reagents: Polyethylene glycol-based reagents used in chemical modification, biomolecular research, and related applications.
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Protecting Groups, Alkylating, Acylating and Related Reagents: Specialized chemical reagents used in organic synthesis, molecular modification, and peptide chemistry.
This broad selection extends beyond standard peptide synthesis materials and provides access to complementary products for researchers working in chemical biology, molecular sciences, and biotechnology.
Quality Assurance, Purity and Product Traceability
The quality of peptide synthesis reagents is essential for achieving consistent experimental results. Even small variations in reagent purity, moisture content, or chemical composition can influence reaction performance and the quality of the resulting synthetic peptide.
At AGTC Bioproducts, products are purified to high standards appropriate for their intended synthesis applications.
Water content is minimized in our solvents, and containers are purged with nitrogen and sealed to help protect their contents from atmospheric exposure. These handling measures are particularly relevant for moisture-sensitive materials and contribute to maintaining product quality throughout storage.
cGMP-standard products are also available, offering additional options for customers with specific quality and manufacturing requirements.
Products can be supplied in bulk quantities to accommodate different laboratory, production, and manufacturing needs.
For bulk FMOC amino acid products used in production, Proton Nuclear Magnetic Resonance (¹H NMR) and mass spectrometry (MS) analyses are provided as a standard feature on individual 10-kilogram packs. These analytical techniques provide additional assurance regarding the identity and composition of the supplied materials.
Proton NMR provides structural information based on the chemical environment of hydrogen atoms within a molecule, while mass spectrometry provides information related to molecular mass and helps support compound identification.
Together, these analytical methods complement the company's quality analysis procedures and provide customers with additional confidence that the materials supplied correspond to the required chemical products.
Bulk Quantities and Custom Product Requests
Different research and manufacturing activities require different product quantities. While some laboratories need small quantities of individual reagents for experimental investigations, other customers require larger volumes for production and ongoing synthesis operations.
AGTC Bioproducts can supply products in bulk quantities, providing flexibility for customers with different purchasing and operational requirements.
We also understand that specialized peptide chemistry sometimes requires materials that are not immediately visible in a standard catalogue. If you cannot find a particular amino acid derivative, coupling reagent, resin, linker, solvent, or other peptide-related product, our team encourages you to contact us.
If the product you require is not listed, please ask us and we will work to source it for you.
Explore Our Peptide Synthesis Product Categories
Our extensive product portfolio is organized into specialized categories to help researchers identify the reagents, materials, and services required for their experiments.
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FMOC Amino Acids: Protected amino acid building blocks for solid-phase peptide synthesis.
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Contract Peptide Synthesis: Customized peptide production services based on specific sequence requirements.
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Coupling Reagents for Peptide Synthesis: Reagents supporting peptide bond formation and amino acid coupling.
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Solvents, Scavengers and Liquid Reagents: Essential liquids and chemical materials for peptide synthesis workflows.
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Building Blocks and Peptidomimetics: Specialized molecular building blocks and peptide-inspired compounds.
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Resins: Solid supports used in solid-phase peptide synthesis.
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Loaded Resins: Resins containing pre-attached starting amino acids or other suitable components.
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Carbohydrates: Carbohydrate products for biochemical and molecular research.
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Solid-Phase Linkers: Linker materials connecting peptide chains to solid supports.
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Coupling and Additives: Additional reagents supporting peptide coupling reactions and synthesis procedures.
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Biochemical Tools: Specialized products for biochemical investigations.
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Immobilized Enzymes and Special Proteins: Products for enzyme-related and protein research.
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Natural Products and Biochemistry Tools: Research materials for biochemical studies.
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PEG Reagents: Polyethylene glycol-based reagents for chemical and biomolecular applications.
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Protecting Groups, Alkylating, Acylating and Related Reagents: Chemical reagents for molecular modification and synthesis.
Find the Peptide Synthesis Products You Need
AGTC Bioproducts provides several convenient ways to explore its extensive peptide synthesis and biochemical product catalogue.
Use the navigation links on the left-hand side of the website to browse individual product categories and discover the available reagents, resins, linkers, amino acid derivatives, and related materials.
Alternatively, enter the product name or CAS number into our search box to locate a specific chemical compound or laboratory reagent.
For peptide products, our quick search function offers an additional convenient option. With more than 400 ready-made and commonly used peptides in our inventory, researchers can simply enter a complete peptide sequence or a portion of the sequence to identify matching products.
Customers looking for a peptide that is not available in our existing stock can request a quotation for a custom synthesized peptide prepared according to their requirements.
For a more comprehensive overview of the available products, you can also view and download a hard copy of our full peptide product catalogue in PDF format.
AGTC Bioproducts Ltd – Your Partner for Peptide Synthesis and Research Reagents
From FMOC amino acids and coupling reagents to specialized resins, solvents, linkers, and custom synthesized peptides, AGTC Bioproducts offers a comprehensive range of products for peptide chemistry and life science research. for more information
Our extensive catalogue combines essential peptide synthesis building blocks with complementary biochemical tools, ready-made peptide products, and custom synthesis services.
Whether you are performing routine solid-phase peptide synthesis, investigating peptide structure and biological activity, developing specialized peptide sequences, or sourcing bulk quantities of production reagents, our portfolio is designed to support a wide variety of research and manufacturing requirements.
With a focus on reagent quality, suitable product handling, analytical assurance for bulk FMOC products, and a broad selection of available materials, AGTC Bioproducts aims to make peptide synthesis products and specialized research reagents accessible to the scientific community.
Explore our peptide synthesis reagents, discover our range of more than 400 ready-made peptides, or contact AGTC Bioproducts Ltd to discuss your custom peptide synthesis requirements.