RNASE3ECP(Alpha Crosslaps) Introduction

Eosinophil cationic protein (ECP) also known as ribonuclease 3 is a basic protein located in the eosinophil primary matrix.[3] In humans, the eosinophil cationic protein is encoded by the RNASE3 gene. ECP is released during degranulation of eosinophils. This protein is related to inflammation and asthma because in these cases, there are increased levels of ECP in the body. There are three glycosolated forms of ECP and consequently ECP has a range of molecular weights from 18-22 kDa. Eosinophil cationic protein and the sequence related eosinophil-derived neurotoxin (RNASE2) are both members of the ribonuclease a superfamily. Both proteins possess neurotoxic, helmintho-toxic, and ribonucleo-lytic activities. Eosinophil cationic protein is localized to the granule matrix of the eosinophil.

Human RNASE3ECP(Ribonuclease A3Eosinophil Cationic Protein) ELISA Kit Test method

This kit uses sandwich ELISA to detect the concentration of RNASE3ECP(Ribonuclease A3Eosinophil Cationic Protein). RNASE3ECP ELISA Kit allows for the in vitro quantitative determination of RNASE3ECP(Ribonuclease A3Eosinophil Cationic Protein) concentrations in serum, plasma, tissue homogenates and other biological fluids. 

Reference:

1，GRCh38: Ensembl release 89: ENSG00000169397 - Ensembl, May 2017

2， "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

3， Boix E, Carreras E, Nikolovski Z, Cuchillo CM, Nogués MV (June 2001). "Identification and characterization of human eosinophil cationic protein by an epitope-specific antibody". J. Leukoc. Biol. 69 (6): 1027–35. PMID 11404391.