Recombinant Monkeypox Virus A30L Protein [His] (DAG-WT763)

Introduction

Monkeypox virus (MPV or MPXV) is a double-stranded DNA virus that causes monkeypox in
humans and other animals. It belongs to the genus Orthopoxvirus in the family Poxviridae. It is
one of the human orthopoxviruses that includes variola (VARV), cowpox (CPX), and vaccinia
(VACV) viruses. It is not a direct ancestor to, nor a direct descendant of, the variola virus, which
causes smallpox. Monkeypox disease is similar to smallpox, but with a milder rash and lower
mortality rate. Variation in virulence of the virus has been observed in isolates from Central
Africa, where strains are more virulent than those from Western Africa. The two areas have
distinct clades of the virus, termed Congo Basin (Central African) and West African clades.

Keywords

Monkeypox virus; MPXV; Orthopoxvirus; Poxvirus