SLAMF1 Antibody

SLAMF1 Antibody | 6247 | ProSci

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: SLAMF1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SLAMF1.
The immunogen is located within amino acids 30 - 80 of SLAMF1.

Research Area: Stem Cell

Tested Application: E, WB, IHC-P, IF

Application: SLAMF1 antibody can be used for detection of SLAMF1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: 4 isoforms of SLAMF1 are known to exist; this antibody will is predicted to recognize all 4 isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members.

Positive Control 1: Cat. No. 1472 - Rat Colon Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: SLAMF1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SLAMF1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SLAMF1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: SLAMF1 Antibody: SLAM, CD150, CDw150, SLAM, Signaling lymphocytic activation molecule

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SLAMF1 Antibody: The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP) .