TMIGD2 Antibody

TMIGD2 Antibody | 7617 | ProSci

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: TMIGD2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TMIGD2.
The immunogen is located within the last 50 amino acids of TMIGD2.

Research Area: Stem Cell

Tested Application: E, WB, IHC-P

Application: TMIGD2 antibody can be used for detection of TMIGD2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Specificiy: TMIGD2 antibody is human and mouse reactive. At least three isoforms of TMIGD2 are known to exist; this antibody will detect all three. TMIGD2 antibody is predicted to not cross-react with TMIGD1.

Positive Control 1: Cat. No. 1408 - Mouse Small Intestine Tissue Lysate

Positive Control 2: Cat. No. 11-801 - Human Small Intestine Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 31 kDa
Observed: 26 kDa

Validation: N/A

Isoform: N/A

Purification: TMIGD2 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: TMIGD2 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: TMIGD2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: TMIGD2 Antibody: IGPR1, IGPR-1, IGPR1, UNQ3059/PRO9879, Transmembrane and immunoglobulin domain-containing protein 2, Immunoglobulin and proline-rich receptor 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: TMIGD2 (transmembrane and immunoglobulin domain containing 1) , also known as immunoglobulin-containing and proline-rich receptor 1 (IGPR1) , is novel adhesion molecule that is expressed in multiple tissues, primarily in cells of epithelium and endothelium origins (1) . TMIGD2 is thought to be involved in angiogenesis and regulates cellular morphology, homophilic cell aggregation, and cell-cell interaction. TMIGD2 activity also modulates actin stress fiber formation and focal adhesion and reduces cell migration (1) .