ProSci

IL6 Antibody | 15-666

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15-666
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  • IL6 Antibody | 15-666
  • IL6 Antibody | 15-666
  • IL6 Antibody | 15-666
  • IL6 Antibody | 15-666
  • IL6 Antibody | 15-666
  • IL6 Antibody | 15-666
€332.83

Description

IL6 Antibody | 15-666 | ProSci

 

Host: Rabbit

 

Reactivity: Human, Mouse, Rat

 

Homology: N/A

 

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-212 of human IL6 (NP_000591.1) .

 

Research Area: Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity, Neuroscience, Obesity

 

Tested Application: WB, IF

 

Application: WB: 1:200 - 1:2000
IF: 1:50 - 1:200

 

Specificiy: N/A

 

Positive Control 1: THP-1

 

Positive Control 2: Mouse spleen

 

Positive Control 3: Rat spleen

 

Positive Control 4: N/A

 

Positive Control 5: N/A

 

Positive Control 6: N/A

 

Molecular Weight: Observed: 27kDa

 

Validation: N/A

 

Isoform: N/A

 

Purification: Affinity purification

 

Clonality: Polyclonal

 

Clone: N/A

 

Isotype: IgG

 

Conjugate: Unconjugated

 

Physical State: Liquid

 

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

 

Concentration: N/A

 

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

 

Alternate Name: Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2

 

User Note: Optimal dilutions for each application to be determined by the researcher.

 

BACKGROUND: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.

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Additional Information

Clonality:
Polyclonal
Tested Applications:
IF, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Size:
50 uL
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