Monobind

17OHP SI AccuLite CLIA Kit

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SKU:
9975-300
Weight:
0 KGS
Shipping:
Calculated at Checkout
€444.40

Description

17-OHP-SI

This test is an alternative to 17-OHP (#5200) for improved  sensitivity and larger measurement range.

17-Hydroxyprogesterone is a C-21 steroid hormone produced in the synthesis of glucocorticoids and sex steroids. As a hormone, 17-OHP also interacts with the progesterone receptor.

Measurements of 17-OHP levels are useful in the evaluation of patients with suspected congenital adrenal hyperplasia (CAH) as the typical enzymes that are defective, namely 21-hydroxylase and 11β-hydroxylase, lead to a build-up of 17-OHP.

In contrast, the rare patient with 17α-hydroxylase deficiency will have very low or undetectable levels of 17-OHP. 17-OHP levels can also be used to measure contribution of progestational activity of the corpus luteum during pregnancy as progesterone but not 17-OHP is also contributed by the placenta.

The application of 17-OHP has been shown to be useful to delay premature labor in pregnancy.

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Additional Information

Method:
Enzyme Immunoassay, Chemiluminescence
Principle:
Competitive, Streptavidin-Coated Plate
Calibrators:
0 , 0.1, 0.5, 1.0, 5, 10, 20 ng/ml
Sample:
25 µl
Sensitivity:
0.03 ng/ml
Reading:
RLU’s
Total Time:
50 Minutes
Shelf Life:
18 Months
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