Anti-PEG monoclonal antibody, Biotin (CABT-L3133)

Mouse Anti-PEG monoclonal antibody, clone 4.4 [Biotin] (CABT-L3133)
This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview :

• This biotin-labeled antibody displays high affinity for the PEG backbone and is especially suitable as a detection antibody for the quantification of PEGylated molecules in conjunctionwith streptavidin-labeled detection agents.
  

Specificity :

• This biotin-labeled antibody displays high affinity for the PEG backbone and is especially suitable as a detection antibody for the quantification of PEGylated molecules in conjunction with  streptavidin-labeled detection agents.
  

Target : Polyethylene glycol
Isotype : IgG1
Source/Host : Mouse
Species Reactivity : N/A
Clone : 4.4
Purification : Affinity Purified
Conjugate : Biotin
Applications : ELISA(Det), WB, FC
Format : Liquid
Concentration : Lot specific
Size : 200 μg

Buffer : PBS
Preservative : 0.1% Sodium Azide
Storage : Store at 2-8°C.
Ship : Wet ice

BACKGROUND
Introduction 

PEG (polyethylene glycol) is a water-soluble, nontoxic, biocompatible polymer that has been approved by the Food and Drug Administration (FDA) for human intravenous, oral and dermal applications. Attachment of PEG chains to proteins can reduce their immunogenicity,
minimize proteolytic cleavage and increase their serum half-life. PEG has also been attached to small molecules and liposomes for more selective delivery. PEG-modification of superparamagnetic iron oxide and quantum dots can improve their biocompatibility and
reduce non-specific uptake.
PEG antibodies can be a vital tool for propelling therapeutics to market by serving as a positive control anti-drug antibody, measuring clearance of a drug, or simply as a QA release confirming PEGylation.
Keywords : Polyetheylene Glycol; PEG