Anti-PEG monoclonal antibody | CABT-L3131

Mouse Anti-PEG monoclonal antibody, clone
BHQ4 (CABT-L3131)
This product is for research use only and is not intended for diagnostic use.BACKGROUND

Introduction :

PEG (polyethylene glycol) is a water-soluble, nontoxic, biocompatible polymer that has been approved by the Food and Drug Administration (FDA) for human intravenous, oral and dermal applications. Attachment of PEG chains to proteins can reduce their immunogenicity, minimize proteolytic cleavage and increase their serum half-life. PEG has also been attached to small molecules and liposomes for more selective delivery. PEG-modification of
superparamagnetic iron oxide and quantum dots can improve their biocompatibility and reduce non-specific uptake.
PEG antibodies can be a vital tool for propelling therapeutics to market by serving as a positive control anti-drug antibody, measuring clearance of a drug, or simply as a QA release confirming PEGylation.
Keywords :

Polyetheylene Glycol; PEG